L-Homoserine
- Product Name
- L-Homoserine
- CAS No.
- 672-15-1
- Chemical Name
- L-Homoserine
- Synonyms
- HOMOSERINE;HSE;(S)-2-AMINO-4-HYDROXYBUTANOIC ACID;H-HOMOSER-OH;H-HSE-OH;H-HOSER-OH;H-HOMOSERINE;(2S)-2-Amino-4-hydroxybutanoic acid;RODH;SDR9C6
- CBNumber
- CB2854094
- Molecular Formula
- C4H9NO3
- Formula Weight
- 119.12
- MOL File
- 672-15-1.mol
L-Homoserine Property
- Melting point:
- 203 °C (dec.)(lit.)
- alpha
- -8.5 º (c=2, H2O 22 ºC)
- Boiling point:
- 222.38°C (rough estimate)
- Density
- 1.3126 (rough estimate)
- refractive index
- 1.4183 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- 1100g/l
- pka
- 2.71(at 25℃)
- form
- Crystalline Powder
- color
- White to light yellow
- Water Solubility
- 1100 g/L (30 ºC)
- Merck
- 14,4739
- BRN
- 1721681
- InChIKey
- UKAUYVFTDYCKQA-VKHMYHEASA-N
- LogP
- -1.289 (est)
- CAS DataBase Reference
- 672-15-1(CAS DataBase Reference)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-44-35-26-28-7-4-3/9
- WGK Germany
- 3
- F
- 10
- HS Code
- 29225000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- H6515
- Product name
- L-Homoserine
- Packaging
- 1g
- Price
- $365
- Updated
- 2024/03/01
- Product number
- H6515
- Product name
- L-Homoserine
- Packaging
- 5g
- Price
- $1720
- Updated
- 2024/03/01
- Product number
- 8.14359
- Product name
- L-(-)-Homoserine
- Purity
- for synthesis
- Packaging
- 1g
- Price
- $147
- Updated
- 2024/03/01
- Product number
- H1030
- Product name
- L-Homoserine
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $62
- Updated
- 2024/03/01
- Product number
- H1030
- Product name
- L-Homoserine
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $204
- Updated
- 2024/03/01
L-Homoserine Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystalline powder
Uses
L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine. It is also used as an internal standard for neurotransmitter analysis and amino acids quantification.
Definition
ChEBI: L-homoserine is the L-enantiomer of homoserine. It has a role as a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite and an Escherichia coli metabolite. It is an enantiomer of a D-homoserine. It is a tautomer of a L-homoserine zwitterion.
Synthesis Reference(s)
Journal of the American Chemical Society, 80, p. 3147, 1958 DOI: 10.1021/ja01545a057
The Journal of Organic Chemistry, 24, p. 1794, 1959 DOI: 10.1021/jo01093a610
General Description
L-Homoserine is a variant of serine with an additional carbon on its side chain.
Biochem/physiol Actions
L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.
Purification Methods
Likely impurities are N-chloroacetyl-L-homoserine, N-chloroacetyl-D-homoserine, L-homoserine, homoserine lactone, homoserine anhydride (formed in strong solutions of homoserine if slightly acidic). It cyclises to the lactone in strongly acidic solution. It crystallises from water by adding 9 volumes of EtOH. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2612-2616 1961, Beilstein 4 IV 3187.]
L-Homoserine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L-Homoserine manufacturers
- Product
- L-Homoserine 672-15-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 5000kg/month
- Release date
- 2021-10-13
- Product
- L-Homoserine 672-15-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 100 tons
- Release date
- 2022-02-18
- Product
- L-Homoserine 672-15-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10